Scientific Hand Charts Collection:
Wolf-Hirschhorn syndrome!
1 Hand Chart for Wolf-Hirschhorn syndrome!
Wolf-Hirschhorn syndrome (WHS), a.k.a. 4p deletion syndrome (4p-), is a developmental disorder characterized by typical craniofacial features, prenatal and postnatal growth impairment, intellectual disability, severe delayed psychomotor development, seizures, and hypotonia.
Prevalence: Present roughly one in 50,000 births.
One hand charts is available for Wolf-Hirschhorn syndrome describing the significance of various typical dermatoglyphics, often combined with a simian line - see picture below.
NOTICE: Individual hand features described below should not get associated in isolation with any theme; only combinations involving multiple hand levels have potential for diagnostic purposes.
Dermatoglyphics in Medical Disorders (1976), p.189;
authors: B. Schaumann & M. Alter
Other significant hand signs (not reported inside the hand charts):
Typical hand behaviors associated with Wolf-Hirschhorn syndrome are: hand flapping, hand washing, holding the hands in front of the face (source: H. Chen et al., 2015).
Small hands are often seen in Wolf-Hirschhorn syndrome (source: NORD).
Small nails, short nails, narrow nails & flat nails [hypoplastic nails] have also been reported for Wolf-Hirschhorn syndrome in various articles.
Clinodactyly (curved-in pinky fingers) is recognized as a common feature in Wolf-Hirschhorn syndrome; in a small study a prevalence of 20% has been reported (source: A. Battaglia et al., 1999).
Other typical finger features are: low-set thumbs, tapered fingers with narrow pink tips (source: W.R. Centerwall et al., 1975). And finger-like appearance of the thumb, and thin fingers with bilateral overriding of the second finger onto the third (source: A. Battaglia et al., 1999).
Ectrodactyly [split hand/cleft hand] is a feature that is seen in a small minority of Wolf-Hirschhorn syndrome cases; prevalence appears close to 2% (source: A.L Shanske et al., 2009).
All significant hand signs listed above for Wolf-Hirschhorn syndrome together cover 6 out of the nine perspectives of the hand as defined according Multi-Perspective Hand Reading (including hand level 1, 3, 5, 7, 8 & 9).
A summary of the most significant hand sign combinations in Wolf-Hirschhorn syndrome is described here:
Decoding the language of the hand:
hand sign combinations in Wolf-Hirschhorn syndrome!
Hand charts are available for many other diagnostic issues;
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